Royal Free London NHS Foundation Trust
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The Royal Free has a three-fold mission: to provide the best possible services for patients, to bring new therapies and insights discovered through research to the bedside as soon as possible and to teach the healthcare professionals of tomorrow.

We are a founder member of UCLPartners, one of five five accredited academic health science systems in the UK. Its purpose is to translate cutting edge research and innovation into measurable health gain for patients and populations - in London, across the UK, and globally.

Our immunology and transplantation programme is designed to understand the role of the human immune system in health and disease and to develop new diagnostic and therapeutic tools for improved disease prevention and treatment. It includes strategies to enhance immune function in patients suffering from viral infection, cancer and immune defects; and efficient immune suppression improves the outcome of autoimmunity and organ transplantation.

To this end, we are creating a multi-million pound research centre which aims to give patients quicker access to the latest innovative therapies for a range of diseases. The Institute of Immunity, Infection and Transplantation, a partnership development between the Royal Free London NHS Foundation Trust and University College London (UCL), will see world-leading research and clinical trials being brought together in a purpose-designed centre at the Royal Free Hospital.

The research taking place concentrates on developing vaccinations, gene therapy and cell therapy to target cancer, chronic infections (such as HIV, viral hepatitis and tuberculosis), auto-immune diseases (including diabetes, scleroderma and inflammatory bowel disease) and rare diseases such as immunodeficiency, haemophilia and amyloidosis, as well as new types of transplantation.

The infectious diseases programme recognises the large burden of morbidity and mortality associated with infectious diseases, a significant problem in an area which imports a large number of infections from around the world. Our population includes the highest incidence of HIV in the UK, and also a resurgence of tuberculosis. We have other significant research programmes, notably into Parkinson's disease and hearing.

Research is funded from a wide range of sources including research councils, charities, the European Union, the NHS and government departments. The trust participates in an extensive range of basic science and clinical trials, working closely with academic institutions and commercial companies.

Recent research news

The RDOC provides information about the organisation's commitment to health R&D and the roles and responsibilities of the different stakeholders in the organisation in delivering these commitments. It is a key aspect of the NIHR Research Support Services (RSS) framework. For more information please visit

page last reviewed: 15 March 2013